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Can CBD Help with OCD? What the Research Tells Us
May
Interest in using CBD (cannabidiol) to support mental health has grown significantly in recent years, particularly for anxiety-driven conditions such as obsessive-compulsive disorder (OCD). While traditional treatments like therapy and medication remain the primary approach, some people are exploring whether CBD might offer additional support.
In this blog, we explore what the latest research says about CBD’s potential effects on OCD, how it may influence brain activity and behaviour, and why some individuals are turning to hemp-based supplements. We also take a closer look at the different types of CBD oils available, including isolate and broad-spectrum, and explain what makes HempWell’s products stand out.
Understanding OCD and the Role of the Endocannabinoid System
The exact causes of OCD remain uncertain, but increasing attention is being paid to the endocannabinoid system (ECS). This network of receptors, enzymes and signalling molecules helps regulate mood, stress response, memory and other functions often disrupted in OCD.
CBD is thought to interact with this system in several ways. It may influence serotonin signalling and support the function of natural cannabinoids like anandamid both of which are implicated in mood and anxiety regulation. This has led scientists to explore CBD’s potential in calming repetitive thought patterns and easing distress.
What the Research Shows
Clinical Trials
Human trials investigating CBD and OCD are limited but growing. In one placebo-controlled study, 14 adults with diagnosed OCD and prior cannabis use were given three different cannabis formulations in a laboratory setting one high in THC, one high in CBD, and one placebo. Across all sessions, participants reported reductions in anxiety and OCD symptoms.
Interestingly, anxiety scores immediately after the placebo dose were lower than after the THC and CBD formulations. While this finding may reflect the participants’ expectations or the setting of the study, it reinforces the complexity of measuring CBD’s effects in real time.
Another observational study involved 87 individuals with OCD using medical cannabis over time. Results were more encouraging: participants reported a 60% reduction in compulsions, a 52% drop in anxiety, and a 49% decrease in intrusive thoughts. Products with higher CBD content were associated with greater improvements.
Though promising, this data is self-reported and uncontrolled. Controlled clinical trials with larger sample sizes are needed to confirm whether these effects are directly due to CBD.
Animal Studies and Mechanistic Research
Preclinical studies using animal models have provided insight into how CBD may affect compulsive behaviour. For instance, in rodent studies, CBD reduced marble-burying and other repetitive behaviours, which researchers use as proxies for compulsions. These effects were sometimes time-dependent and related to dose.
Mechanistically, CBD has been shown to modulate the WNT/β-catenin pathway and influence GABAergic and glutamatergic signalling. These neurotransmitter systems are often disrupted in OCD. Additionally, there’s emerging evidence that CBD’s effect on fear extinction—important in exposure-based therapies—may further support its potential in managing anxiety and intrusive thoughts.
The Entourage Effect
Some researchers propose that CBD works best when combined with other natural compounds found in the hemp plant, such as terpenes and minor cannabinoids. This is known as the “entourage effect.” A 2020 review noted that several cannabis compounds, particularly terpenes, may have anxiolytic properties. Interactions between CBD and these compounds could enhance the overall calming effect.
This supports the use of broad-spectrum CBD oils, which retain a range of non-psychoactive plant compounds while remaining THC-free. Full-spectrum products include small traces of THC, but are not permitted in many UK products due to regulatory limits.
CBD Is Not a Replacement for Therapy
While the early data is encouraging, CBD is not a cure for OCD. Cognitive behavioural therapy (CBT), particularly exposure and response prevention (ERP), remains the gold standard for treatment. Medications such as SSRIs may also be prescribed.
CBD may complement these therapies by supporting general mood and reducing the edge of anxiety, especially in moments of acute stress. However, it should not be relied on as a standalone solution.
HempWell’s CBD Oil: Supporting Mind and Body
At HempWell, we offer a range of CBD products made to high standards here in the UK. Our Broad-Spectrum CBD Oil retains a full profile of naturally occurring cannabinoids and terpenes, but is entirely free from THC. This makes it a popular choice for those seeking the benefits of the entourage effect without psychoactive components.
We also offer CBD Isolate Oils, which contain pure cannabidiol and nothing else. These are ideal for those who prefer a simpler formulation or are subject to strict testing in the workplace or competitive sport.
Our oils are made from organically grown EU hemp and tested in independent labs for quality and consistency. They’re available in a range of strengths and carrier oils, making it easy to find an option that fits your routine.
A Note on Use
Although everyone’s body reacts differently, CBD is generally well-tolerated. Unlike THC, it does not produce a high. If you are exploring CBD as a supplement for OCD-related symptoms, we recommend starting with a lower strength and gradually adjusting as needed. Always speak to a healthcare provider if you’re taking medications or undergoing therapy.
Final Thoughts
CBD’s potential in supporting people with OCD is a topic of growing interest among researchers. Early studies suggest that it may reduce anxiety, support emotional regulation, and modulate systems involved in compulsive behaviour. However, the current evidence base is still developing, and more robust trials are needed to confirm its role in clinical care.
For those already managing OCD with therapy or medication, CBD may offer a gentle, natural way to support wellbeing and manage daily stress. At HempWell, we’re committed to offering high-quality, trustworthy products rooted in science and manufactured with care.
Disclaimer:
This article is based on current research and is intended for informational purposes only. CBD is not a medical treatment and should not replace professional therapies or medication. Please consult a healthcare provider before beginning any new supplement.
Sources:
- https://pubmed.ncbi.nlm.nih.gov/32383271/
- https://releaf.co.uk/education/medical/psychiatric/ocd/how-to-take-cbd-oil-for-ocd-symptom-relief
- https://www.medicalnewstoday.com/articles/cbd-for-ocd#Pros-and-cons
- https://www.treatmyocd.com/blog/does-cbd-and-marijuana-help-with-ocd
- https://www.healthline.com/health/ocd/cbd-for-ocd#cbd-for-ocd
